The use of Sodium Butyrate in preventing colon diseases


 

Diarrhoea & Gut Inflammation

Alcohol consumption harms our stomach; butyrate prevents inflammation & stomach ulcers.

Sodium butyrate combined with other SCFAs and silicon dioxide can benefit traveller’s diarrhoea. Traveller’s diarrhoea is more common among those who travel to exotic countries.

In multiple studies, it has been observed that butyrate is helpful for healthy gut flora, controlling people’s inflammation, and maintaining a strong intestinal barrier.

Butyric prevents Colon Cancer

Butyric acid is widely preferred for the colonic enterocyte. Several potential anti-cancer properties are found.

An increase in the rate of colonic cell proliferation is believed to be a risk factor for cancer. However, all cells in the colon are programmed with a time to die by a controlled process called apoptosis.

It is probably the balance between apoptosis and the levels of proliferation and that determine whether a cancer will or will not develop.

Although butyrate has been shown to stimulate cell proliferation of normal colonic cells, it has been shown to stimulate apoptosis in cancer cells in vitro.

Butyrate is a major short-chain fatty acid produced during gut flora-mediated fermentation of dietary fibres. Legumes (peas, beans, and soybeans), fruits, cereals, nuts, and whole grains are good sources of dietary fibres. Butyrate is also found in cheese and butter.

It may also affect other important stages in carcinogenesis such as the promotion of cell differentiation and inhibition of histone deacetylase, which may promote DNA repair.

Product: Sodium Butyrate

Pharmacopea: USP

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